Nanotechnology in drug delivery

How is nanotechnology used in drug delivery?

Perhaps the most publicized use of nanotechnology in drug delivery under development is the use of nanoparticles to deliver drugs to cancer cells. Particles are engineered so that they are attracted to diseased cells, which allows direct treatment of those cells.

Which nanoparticles are used in drug delivery?

Nanoparticles used in drug delivery system Chitosan. Chitosan exhibits muco-adhesive properties and can be used to act in the tight epithelial junctions. Alginate. Xanthan gum. Cellulose. Liposomes . Polymeric micelles. Dendrimers . Inorganic nanoparticles.

What is Nano drug delivery system?

Nano – drug delivery systems (NDDSs) are a class of nanomaterials that have abilities to increase the stability and water solubility of drugs, prolong the cycle time, increase the uptake rate of target cells or tissues, and reduce enzyme degradation, thereby improve the safety and effectiveness of drugs (Quan et al.,

What is a drug delivery device?

Drug delivery devices are specialized tools for the delivery of a drug or therapeutic agent via a specific route of administration . Such devices are used as part of one or more medical treatments.

What are the disadvantages of nanotechnology?

Nanotechnology offers the potential for new and faster kinds of computers, more efficient power sources and life-saving medical treatments. Potential disadvantages include economic disruption and possible threats to security, privacy, health and the environment.

Who invented nanomedicine?

In fact, Nanomedicine can be traced back to the use of colloidal gold in ancient times [6,7], but Metchnikov and Ehrlich (Nobel Prize for Medicine in 1908) are the modern pioneers of nanomedicine for their works on phagocytosis [8] resp.

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What is the advantage of nano drug delivery?

The important technological advantages of nanoparticles used as drug carriers are high stability , high carrier capacity, feasibility of incorporation of both hydrophilic and hydrophobic substances, and feasibility of variable routes of administration, including oral application and inhalation.

Is Nanomedicine being used today?

Nanotechnology in Medicine Application: Drug Delivery One application of nanotechnology in medicine currently being developed involves employing nanoparticles to deliver drugs, heat, light or other substances to specific types of cells (such as cancer cells). Read more about nanomedicine in drug delivery.

Why are nanoparticles used for drug delivery?

Due to their small size and large surface area, drug nanoparticles show increase solubility and thus enhanced bioavailability, additional ability to cross the blood brain barrier (BBB), enter the pulmonary system and be absorbed through the tight junctions of endothelial cells of the skin (Kohane, 2007).

What are the types of nanoparticles?

Nanoparticles can be classified into different types according to the size, morphology, physical and chemical properties . Some of them are carbon-based nanoparticles, ceramic nanoparticles, metal nanoparticles , semiconductor nanoparticles , polymeric nanoparticles and lipid-based nanoparticles.

How does drug delivery work?

Drug delivery refers to the technology utilized to present the drug to the desired body site for drug release and absorption, or the subsequent transport of the active ingredients across the biological membranes to the site of action.

What are nanoparticles made of?

The definition given by the European Commission states that the particle size of at least half of the particles in the number size distribution must measure 100 nm or below. Most nanoparticles are made up of only a few hundred atoms.

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What are the 4 drug delivery methods?

Current research on drug delivery systems can be described in four broad categories: routes of delivery, delivery vehicles , cargo, and targeting strategies. Medications can be taken in a variety of ways—by swallowing, by inhalation , by absorption through the skin, or by intravenous injection.

What are the 8 routes of drug administration?

Oral route. Many drugs can be administered orally as liquids, capsules, tablets, or chewable tablets. Injection routes. Administration by injection (parenteral administration) includes the following routes: Sublingual and buccal routes. Rectal route . Vaginal route. Ocular route. Otic route. Nasal route.

What is new drug delivery system?

Drug delivery systems (DDSs) are developed to deliver the required amount of drugs effectively to appropriate target sites and to maintain the desired drug levels. Research in newer DDS is being carried out in liposomes, nanoparticles, niosomes, transdermal drug delivery , implants, microencapsulation, and polymers.